Variants:
1488
Reviews
Craft Holsters - Holsters - Colt Holsters - Colt Python 4.25 Inch Holsters
Left Handed Holsters for Colt Python 4.25 Inch
How To Choose The Best Left Handed Holster For Your Colt Python - 4.25" (Post 2020)
When you're shopping for a new holster for you.Colt Python - 4.25" (Post 2020), knowing exactly what you want matters. If you've narrowed it down to a holster, you're already on the right path. Below, we’ll walk you through why this carry style might be the ideal fit, how to find the best model for your body type and setup, and what materials and add-ons to consider.
WhyChoosea Colt Python - 4.25" (Post 2020) Left-Handed Holster?
Left-handed holsters are designed specifically for left-handed shooters, ensuring a natural, safe, and efficient draw. They excel in everyday carry, duty use, and range training for left-handed users.
Perfect for left-handed draw
These holsters are built for a smooth, intuitive draw with your left hand, enhancing confidence and speed in defensive situations.
Custom made for your setup
Our holsters are molded directly to your Colt Python - 4.25" (Post 2020), guaranteeing a precise fit, secure retention, and proper draw angle for left-handed carry.
Ideal for EDC, duty, or training
Whether for daily concealed carry, professional duty, or range practice, left-handed holsters provide comfort, accessibility, and safety tailored to your draw style.
How to Choose the Right Colt Python - 4.25" (Post 2020) Left-Handed Holster
Carry style and fit
Choose IWB for concealment, OWB for open carry, or shoulder, chest, or duty setups based on your needs and daily routine.
Handedness compatibility
Ensure the holster is specifically designed for left-handed users, with cant and positioning optimised for your natural draw.
Retention and safety
Select holsters with secure retention systems that keep your firearm in place while allowing a quick, confident left-hand draw.
Choosing the best holster for your Colt Python - 4.25" (Post 2020) comes down to fit, comfort, and confidence. Whether you carry concealed every day or need something rugged for outdoor use, this carry style delivers dependable performance.
Holsters for Colt Python - 4.25" (Post 2020) reviews
59 reviews
Latest reviews
Kevin F.
I’m on my 3rd, Craft, cross draw, holster. The quality, materials and craftsmanship is exceptional. The fit and finish, exceed my expectations. I strongly recommend craft holsters.
08/31/2025
United States
James R.
Having already purchased two holsters from Craft Holsters, a shoulder rig for a Walther P99c 9MM and a second for an H.K. USP in 40 cal, I was well aware of the phenomenal quality of both materials and craftsmanship that Craf Holsters puts into their products. Everything from form to function had been flawless. Having been so impressed with my previous previous purchases I knew right where to go when I needed a holster for my latest addition. I wanted a Kydex OWD right hand draw for Colt Python 4.25 barrel. It would need to (A) hold the weapon securely with out a retention strap, (B) have adjustable hight and cant, and (C) be suitable for not only carry in the three o'clock position but be able to switch to a cross draw position quickly. I knew exactly where to look. To be honest I did check out other websites but found them lacking. With zero hesitation I placed my order with Craft Holsters and waited for my order to arrive. Once I received my order I immediately checked the fit and function and was throughly impressed and pleased with every aspect of my new holster. If / when I need another holster I will not hesitate to order from Craft Holsters again. Quality matters.
08/26/2025
United States
Ellis M.
Very nice holster. A little pricy, but that's OK. You get what you pay for. I ordered the break-in kit, but the holster fit my Colt Python very nicely right out of the box. Customer service is excellent, great communication and extra touches. Highly recommended.
08/04/2025
United States
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Best Gun Holster Accessories
Choose the right accessories below that will enhance your carry. Don't forget that a proper magazine pouch, a belt or a concealed carry bag are always good choices.
MAGAZINE
POUCHES
Get yourself a custom mag pouch or speedloader pouch. Because there is never "enough ammo" right?
See Magazine Pouches
GUN BELTS
A solid and stable gun belt is what you need to prevent your holster and the rest of your EDC from sagging.
See Gun Belts
care kits
Don't forget to get yourself a handy kit that contains everything you need to make sure your holster will last you a lifetime.
See Care Kits
