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Left Handed Holsters for Colt Python 4.25 Inch

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How To Choose The Best Left Handed Holster For Your Colt Python - 4.25" (Post 2020)

When you're shopping for a new holster for you.Colt Python - 4.25" (Post 2020), knowing exactly what you want matters. If you've narrowed it down to a holster, you're already on the right path. Below, we’ll walk you through why this carry style might be the ideal fit, how to find the best model for your body type and setup, and what materials and add-ons to consider.

WhyChoosea Colt Python - 4.25" (Post 2020) Left-Handed Holster?

Left-handed holsters are designed specifically for left-handed shooters, ensuring a natural, safe, and efficient draw. They excel in everyday carry, duty use, and range training for left-handed users.

Perfect for left-handed draw

These holsters are built for a smooth, intuitive draw with your left hand, enhancing confidence and speed in defensive situations.

Custom made for your setup

Our holsters are molded directly to your Colt Python - 4.25" (Post 2020), guaranteeing a precise fit, secure retention, and proper draw angle for left-handed carry.

Ideal for EDC, duty, or training

Whether for daily concealed carry, professional duty, or range practice, left-handed holsters provide comfort, accessibility, and safety tailored to your draw style.

How to Choose the Right Colt Python - 4.25" (Post 2020) Left-Handed Holster

Carry style and fit

Choose IWB for concealment, OWB for open carry, or shoulder, chest, or duty setups based on your needs and daily routine.

Handedness compatibility

Ensure the holster is specifically designed for left-handed users, with cant and positioning optimised for your natural draw.

Retention and safety

Select holsters with secure retention systems that keep your firearm in place while allowing a quick, confident left-hand draw.

Choosing the best   holster for your Colt Python - 4.25" (Post 2020) comes down to fit, comfort, and confidence. Whether you carry concealed every day or need something rugged for outdoor use, this carry style delivers dependable performance.

Holsters for Colt Python - 4.25" (Post 2020) reviews

4.8
49 reviews

Latest reviews

Kevin F.

I’m on my 3rd, Craft, cross draw, holster. The quality, materials and craftsmanship is exceptional. The fit and finish, exceed my expectations. I strongly recommend craft holsters.

08/31/2025 United States

Ellis M.

Very nice holster. A little pricy, but that's OK. You get what you pay for. I ordered the break-in kit, but the holster fit my Colt Python very nicely right out of the box. Customer service is excellent, great communication and extra touches. Highly recommended.

08/04/2025 United States

Riveroh

Excellent quality leather, high quality craftsmanship manufacture holster. This is my 7th holster I have purchased from craft holsters on the COLT web-site.

07/09/2025 United States

Best Gun Holster Accessories

Choose the right accessories below that will enhance your carry. Don't forget that a proper magazine pouch, a belt or a concealed carry bag are always good choices.

MAGAZINE
POUCHES

Get yourself a custom mag pouch or speedloader pouch. Because there is never "enough ammo" right?

See Magazine Pouches

GUN BELTS

A solid and stable gun belt is what you need to prevent your holster and the rest of your EDC from sagging.

See Gun Belts

care kits

Don't forget to get yourself a handy kit that contains everything you need to make sure your holster will last you a lifetime.

See Care Kits

SHOP WITH CONFIDENCE