Craft Holsters - Holsters - Colt Holsters - Colt Python 4.25 Inch Holsters

Black Holsters for Colt Python 4.25 Inch

Colt Python - 4.25" (Post 2020) Black Clear All Filters

Fan Favorite Holsters

Bedside Kydex Holster Setup

$199

It. SET010

0 Reviews

No reviews yet

Belly Band Kydex Holster

$185

It. B105

6 Reviews

5.0

Belt Side Kydex Holster

$145

It. C901

Variants:

Red Dot Ready Light Bearing Light & Red Dot

27 Reviews

4.7

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Kydex Car Holster Setup

$179

It. SET013

0 Reviews

No reviews yet

Kydex IWB Holster w Clip

$145

It. A903

Variants:

Red Dot Ready Light Bearing Light & Red Dot

34 Reviews

4.8

Kydex Paddle Holster

$149

It. C912

Variants:

Red Dot Ready Light Bearing

2 Reviews

3.0

Retention Level 2 Duty Holster Set

$599

It. SET004

0 Reviews

No reviews yet

Velcro Kydex Holster

$125

It. A905

0 Reviews

No reviews yet

Bedside Nylon Holster Setup

$119

It. SET009

0 Reviews

No reviews yet

Canted OWB Nylon Holster

$49

It. C702

134 Reviews

4.8

Drop Leg Nylon Holster

$85

It. E701

Variants:

Red Dot Ready Light Bearing

75 Reviews

4.5

Lowered OWB Duty Nylon Holster

$75

It. C711

54 Reviews

4.5

Nylon Ankle Gun Holster

$69

It. 455

20 Reviews

4.4

Nylon Car Holster Setup

$95

It. SET012

0 Reviews

No reviews yet

Nylon Chest Holster

$89

It. D710

98 Reviews

4.6

Nylon Cross Draw Gun Holster

$59

It. C826

141 Reviews

4.4

Nylon Elastic Ankle Holster

$35

It. 507

12 Reviews

4.3

Nylon IWB Holster

$45

It. A701

Variants:

Red Dot Ready Light Bearing Light & Red Dot

114 Reviews

4.7

Nylon Paddle Holster

$109

It. C714

41 Reviews

4.8

Nylon Roto Shoulder Holster System

$179

It. D709/22

Variants:

Red Dot Ready Light Bearing

31 Reviews

3.9

Nylon Shoulder Holster System

$165

It. D701/22

Variants:

Red Dot Ready

55 Reviews

4.3

Velcro Nylon Holster

$39

It. A709

11 Reviews

5.0

How To Choose The Best Holster For Your Colt Python - 4.25" (Post 2020)

When you're shopping for a new holster for you.Colt Python - 4.25" (Post 2020), knowing exactly what you want matters. If you've narrowed it down to a holster, you're already on the right path. Below, we’ll walk you through why this carry style might be the ideal fit, how to find the best model for your body type and setup, and what materials and add-ons to consider.

Choosing the best holster for your Colt Python - 4.25" (Post 2020) comes down to fit, comfort, and confidence. Whether you carry concealed every day or need something rugged for outdoor use, this carry style delivers dependable performance.

Holsters for Colt Python - 4.25" (Post 2020) reviews

4.0

4 reviews

Latest reviews

James R.

Having already purchased two holsters from Craft Holsters, a shoulder rig for a Walther P99c 9MM and a second for an H.K. USP in 40 cal, I was well aware of the phenomenal quality of both materials and craftsmanship that Craf Holsters puts into their products. Everything from form to function had been flawless. Having been so impressed with my previous previous purchases I knew right where to go when I needed a holster for my latest addition. I wanted a Kydex OWD right hand draw for Colt Python 4.25 barrel. It would need to (A) hold the weapon securely with out a retention strap, (B) have adjustable hight and cant, and (C) be suitable for not only carry in the three o'clock position but be able to switch to a cross draw position quickly. I knew exactly where to look. To be honest I did check out other websites but found them lacking. With zero hesitation I placed my order with Craft Holsters and waited for my order to arrive. Once I received my order I immediately checked the fit and function and was throughly impressed and pleased with every aspect of my new holster. If / when I need another holster I will not hesitate to order from Craft Holsters again. Quality matters.

08/26/2025 United States

Tony M.

Looks good but needs improvement in lower leg strap is way to short. I'm 145 lbs and slender and it's not adjustable enough even for me. The upper leg stap is adjusted to max and it barely is enough. Also the drop section below the belt loop buckle release is crap. Just a couple off folds of material held together with inadequate piece of Velcro. Also the holster with gun during walking, the gun flops back and forth. If the leg straps were sewed to the holster in a different way,this would solve this problem. I spent an extra $20 at the local seamstress to beef in up in a couple of areas,and it is still a peace of POOP! I just put the whole thing in my gun parts box (junk box) and call this purchase a complete failure.

05/05/2025 United States

David H.

Great fit. Holds great on my waist band and belt. Top Quality. Well worth the wait of construction!! The Best!!

04/22/2024 United States

Need a Holster for Another Colt?

Best Gun Holster Accessories

Choose the right accessories below that will enhance your carry. Don't forget that a proper magazine pouch, a belt or a concealed carry bag are always good choices.

MAGAZINE
POUCHES

Get yourself a custom mag pouch or speedloader pouch. Because there is never "enough ammo" right?

See Magazine Pouches

GUN BELTS

A solid and stable gun belt is what you need to prevent your holster and the rest of your EDC from sagging.

See Gun Belts

care kits

Don't forget to get yourself a handy kit that contains everything you need to make sure your holster will last you a lifetime.

See Care Kits

Best Light / Laser Bearing Holsters

Light bearing holsters are built for shooters who need secure carry without giving up their weapon-mounted light or laser. Our selection of light bearing holsters is designed to fit popular attachments from Streamlight, SureFire, Olight, Holosun, Viridian, SIG Sauer, Inforce, Nightstick, and more, while still delivering reliable retention, comfort, and everyday practicality across multiple carry styles.

If you prefer traditional carry without a weapon-mounted light or laser, you can explore our most popular classic holster styles. These include proven carry options such as shoulder leather holsters, OWB and IWB holsters, chest holsters, paddle holsters, cross draw holsters, pocket holsters, duty holsters, and other concealed carry designs. Each style offers a different balance of accessibility, concealment, and comfort, allowing shooters to choose the carry method that best fits their firearm, daily routine, and personal preference.

Shoulder Leather Holsters
Shoulder Nylon Holsters
OWB Leather Holsters
OWB Kydex Holsters
Chest Leather Holsters
Chest Nylon Holsters
IWB Leather Holsters
IWB Kydex Holsters
Concealed Carry Leather Holsters
Concealed Carry Kydex Holsters
Drop Leg Kydex Holsters
Paddle Leather Holsters
Paddle Kydex Holsters
Cross Draw Leather Holsters
Pocket Leather Holsters
Duty Leather Holsters
Duty Kydex Holsters

LIGHT BEARING HOLSTERS

Black Holsters for Colt Python 4.25 Inch

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How To Choose The Best Holster For Your Colt Python - 4.25" (Post 2020)