


The Colt Python 4.25" is a modern iteration of one of Colt's most legendary revolvers, known for its exceptional craftsmanship, smooth trigger action, and unrivaled accuracy. Originally introduced in 1955, the Colt Python quickly gained a reputation as the finest production revolver ever made. After a hiatus, Colt reintroduced the Python in 2020, staying true to its premium heritage while incorporating modern manufacturing enhancements.
Built with a 4.25-inch barrel, .357 Magnum caliber, and a six-round cylinder, the Colt Python 4.25" is designed for precision shooting, target practice, and self-defense. Its full stainless-steel construction, refined trigger, and updated internal components ensure durability and smooth operation. The vented rib barrel and recessed target crown contribute to improved accuracy, while its weight helps manage recoil for more comfortable shooting. With a price typically around $1,500-$1,700, the Colt Python price reflects its status as a premium revolver for enthusiasts and collectors.
Colt Python 4.25": Background & First Impressions
The moment I picked up the Colt Python 4.25", it was clear that this Colt revolver is in a league of its own—its weight feels substantial yet balanced, and the ergonomics of the grip provide a natural, confident hold. The Colt Python has a rich history dating back to 1955, when Colt set out to create the ultimate .357 Magnum revolver, one that would define smooth trigger action, pinpoint accuracy, and premium craftsmanship. After a long hiatus, Colt reintroduced the Python in 2020, bringing back its legendary design with modern refinements to meet today’s standards.
Like its predecessors, the Colt Python 4.25" features stainless steel construction, a vented rib barrel, and an ultra-smooth trigger, but with improved materials and internal upgrades for enhanced durability and reliability. Right out of the box, this Colt revolver exudes precision and power, making it one of the finest factory-produced Colt revolvers available today.
Main SPECS OF COLT PYTHON 4.25

The Colt Python boasts a 4.25-inch barrel, contributing to its exceptional accuracy and balanced handling. With an overall length of 9.75 inches and weighing 42 ounces when unloaded, it strikes a perfect equilibrium between maneuverability and stability. Its six-round cylinder capacity and .357 Magnum chambering ensure reliable performance and formidable stopping power. You can also check all the main specifications of this revolver below:
- Model Name: Colt Python 4.25
- Caliber: .357 Magnum
- Action: Revolving Chamber
- Weight (Unloaded): 42 oz.
- Capacity: 6 rounds
- Overall Length: 9.75 inches
- Overall Width: 1.55 inches
- Overall Height: 5.5 inches
- Barrel Length: 4.25 inches
- Frame Material: Stainless steel
- Safety: transfer bar
- Sights: Adjustable Rear Sight, Front Blade Sight
- MSRP: $1,499
COLT PYTHON REVIEW - PRECISION AT ITS CORE
What really sets the Colt Python 4.25 apart from the competition? It's its precision. I've had the pleasure of putting this beauty through its paces on the range, and I have to say, I've been blown away by its accuracy.
Whether I'm shooting targets at various distances or running through drills, the Colt Python 4.25 consistently delivers tight groupings and predictable performance. It's like the revolver has a built-in GPS for your bullets – they always seem to find their way exactly where you want them to go.
I remember when I was competing in a local shooting competition. With the Colt Python 4.25 in hand, I was able to outshoot competitors using more modern firearms, much to their surprise. It just goes to show that when it comes to accuracy, nothing beats a well-tuned revolver like the Colt Python 4.25.
COLT PYTHON 4.25 REVIEW - PERFORMANCE ON THE RANGE
Of course, precision is only part of the equation – performance is equally important. Fortunately, the Colt Python 4.25 doesn't disappoint in that department either.
Thanks to its balanced weight distribution and ergonomic grip, the Colt Python 4.25 feels like an extension of your arm. Whether you're shooting off-hand or from a supported position, the revolver handles like a dream, allowing you to stay on target with ease.
Practicing rapid-fire drills with the Colt Python 4.25 was like a dream. Despite the fast pace, the revolver remained incredibly stable, allowing me to maintain accuracy even under pressure. It's moments like these that really showcase the Colt Python 4.25's performance capabilities.
HOLSTER COMPATIBILITY AND ACCESSORIES
Now, let's talk about the practical side of things – holster compatibility and accessories. After all, what good is a great revolver if you can't carry it comfortably?
When it comes to finding the right holster for the Colt Python 4.25, you have plenty of options to choose from. Personally, I prefer a snug leather holster that keeps the revolver secure against my hip, but there are also high-quality Kydex options available for those who prefer a more modern look. If you're looking for top-notch craftsmanship and durability, Craft Holsters offers a range of quality holsters specifically designed for the Colt Python 4.25, ensuring both security and style.
As for accessories, the Colt Python 4.25 doesn't require much to shine. However, a good set of grips can make a world of difference in terms of comfort and control. I've experimented with a few different grip options, and I've found that a slightly oversized grip with a textured surface works best for me.
Why Choose the Colt Python 4.25" Over Other Handguns?
The Colt Python 4.25" stands out among Colt revolvers and other handguns due to its legendary craftsmanship, precision engineering, and premium build quality. With its .357 Magnum chambering, the Python delivers powerful stopping power, while the 4.25-inch barrel strikes the perfect balance between accuracy, recoil control, and maneuverability. Whether for target shooting, home defense, or collection purposes, the Python 4.25" offers a superior shooting experience.
Compared to other medium-frame revolvers, the Colt Python 4.25" features an ultra-smooth trigger pull, robust stainless-steel construction, and refined action that make it one of the best-performing revolvers on the market. Its vented rib barrel and recessed target crown enhance accuracy and durability, while its modernized internal components ensure long-term reliability. As a revival of a legendary design, the Colt Python 4.25" remains a top-tier revolver, combining classic aesthetics with cutting-edge performance.
How does Colt Python 4.25 differ from Colt Python 6 inch?
The Colt Python 4.25" and 6" models are both premium Colt revolvers, known for their legendary craftsmanship, smooth action, and .357 Magnum stopping power. However, their barrel lengths create noticeable differences in handling, accuracy, and purpose.
The Colt Python 4.25" strikes a balance between accuracy and maneuverability, making it a versatile choice for self-defense, target shooting, and everyday carry. Its shorter barrel improves draw speed and handling, while still offering excellent accuracy.
On the other hand, the Colt Python 6" is designed with precision shooting in mind. The longer barrel provides superior sight radius and reduced recoil, making it ideal for competition shooting and hunting. However, its increased length and weight can make it less practical for concealed carry or fast handling.
In the Colt Python 4.25" vs 6" debate, it comes down to use case—if you need a well-balanced revolver for both carry and accuracy, the 4.25-inch model is a great option. But if maximum precision and reduced recoil are your top priorities, the 6-inch Python is the better pick.
How does Colt Python 4.25 differ from Colt Python 3 inch?
The Colt Python 4.25" and 3" models cater to different needs, with the 3-inch version prioritizing concealability and the 4.25-inch offering a more balanced shooting experience.
The Colt Python 4.25" is an excellent all-around revolver, providing solid accuracy, manageable recoil, and smooth trigger action. Its slightly longer barrel improves ballistics and control, making it a great choice for home defense, range shooting, and carry.
The Colt Python 3", however, is a more compact version, designed for easier carry and maneuverability. While it still retains the Python’s legendary trigger and build quality, the shorter barrel results in increased muzzle flip and slightly reduced accuracy at longer distances.
In the Colt Python 4.25" vs 3" debate, the 3-inch model is ideal for those who prioritize compact size for carry or defense, while the 4.25-inch version offers a better balance of accuracy, recoil control, and versatility.
COLT PYTHON 4.25 INCH - FAQ
The Colt Python with a 4.25-inch barrel typically weighs approximately 42 ounces when unloaded. This weight contributes to its balance and stability during shooting, making it comfortable to handle and accurate in performance.
There are several reasons why enthusiasts choose to invest in a Colt Python 4.25. Firstly, its reputation for unparalleled precision and accuracy sets it apart as a top-tier revolver in the firearms community. The craftsmanship and build quality of the Python are second to none, ensuring reliability and longevity. Additionally, its timeless design and historical significance make it a coveted piece for collectors. Whether for recreational shooting, self-defense, or as a valuable addition to a firearm collection, the Colt Python offers unmatched performance and prestige.
Colt Pythons 4.25 are beloved by a diverse range of individuals, including law enforcement officers, competitive shooters, firearm enthusiasts, and collectors. Law enforcement agencies have historically favored the Python for its reliability and accuracy in duty use. Competitive shooters appreciate its precision and smooth trigger action, which can give them an edge in shooting competitions. Enthusiasts and collectors are drawn to the Python for its iconic design, historical significance, and reputation as one of the finest revolvers ever made. Whether for practical use or admiration of its craftsmanship, the Colt Python appeals to a wide audience of firearm aficionados.
COLT PYTHON 4.25 REVIEW - FINAL VERDICT

The Colt Python 4.25 is everything you could want in a revolver and more. Its precision, performance, and timeless design make it a standout choice for both seasoned shooters and newcomers alike.
Whether you're hitting the range for target practice or carrying for self-defense, the Colt Python 4.25, paired with a quality Colt Python 4.25 holster, offers unmatched performance and reliability that will leave a lasting impression on anyone who has the pleasure of experiencing it.